This module encompasses modern aspects of protein structure and function and shows how chemical and biological properties can be related to both three-dimensional structure and post-translational modifications. Topics include purification and characterisation of proteins, X-ray crystallography and NMR methods, structural motifs and families, unfolding and folding, enzyme mechanisms and enzyme technology. Approaches in protein engineering, protein conformations, predictions from sequence data and mutational effects on folding will also be covered. The molecular basis of drug action and site-directed drug design will be explained.
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Administrative assistant: RAINA FERHANA HOSSENBUX
Telephone: 4037400
Email: r.hossenbux@uom.ac.mu |