The formed elements of blood and an introduction to the physiology of plasma proteins, including a classification of blood cells and the role of plasma proteins in exerting plasma oncotic pressure. Haematopoiesis, including the monophyletic origin of blood cells, renewal by pluripotential stem cells, erythropoiesis and granulopoiesis, regulation by glycoprotein growth factors. Aplastic anaemia and acute leukaemia as examples of bone marrow failure. The concept of anaemia, including the structure and function of the erythrocyte, the biochemistry and physiology of haemoglobin, normal and abnormal, and its role in oxygen carriage. Simple deficiency disorders, including deficiencies in iron, folate and vitamin B12. Homeostasis, including the biology of platelets and the clotting factor cascade. Fibrinolysis, including clot dissolution, clotting disorders and an introduction to anticoagulant therapy. Overview of immunity, including an overview of leucocyte function, phagocytic cells and an introduction to immunoglobulin structure and function. Blood transfusion, including the ABO and rhesus blood groups, and a consideration of transfusion risks. |
Administrative assistant: RAINA FERHANA HOSSENBUX
Telephone: 4037400
Email: r.hossenbux@uom.ac.mu |