The cellular basis of the immune response: lymphocyte functions: T-cell help for antibody responses and microphage activation; T-cell cytotoxicity and the killing of virally infected cells. B-cells and immunoglobulins: antibody mediated effector mechanisms; complex function, opsonisation and complement activation via the classical pathway. Immune regulation: the interleukins.populations, antigen presenting cells and macrophages. Innate immunity: phagocytic functions; intracellular and extracellular killing; humoral factors: complement. Adaptive immunity: the specific, acquired immune response; cell mediated and humoral immune responses. Immunologically relevant molecules: immunoglobulins, T-cell receptors and the MHC gene products. The generation of diversity of antigen receptors. Antigen processing and presentation: exogenous and endogenous pathways. MHC restriction of T-cell response. T-cell activities and effector