Inflammation and immunity: hypersensitivity responses - types I, II, III and IV. Autoimmunity: immune mechanisms of pathogenicity. Organ specific and non-organ specific disease. Immunodeficiency: primary immunodeficiencies and acquired immunodeficiency disorders; hypogammaglobulinaemia; Di George syndrome; SCID; AIDS.Transplantation immunity: self v/s non-self; MHC genes and products; MHC polymorphism, haplotypes and tissue typing. Allogenic responses; cell mediated and humoral mechanisms of rejection. Renal transplantation. Bone marrow transplantation and graft v/s host reactions. Immunotherapy: interleukin and antibody therapies. Immunisation and vaccines.
